费城一个毫无征兆的宁静早晨，前联合国调查员盖瑞·雷恩（布拉德·皮特 Brad Pitt 饰）驾车载着妻子凯伦（米瑞·伊诺丝 Mireille Enos 饰）和两个女儿蕾切尔（Abigail Hargrove 饰）、康妮（Sterling Jerins 饰）外出。谁知原本快乐的气氛很快变为恐慌与死亡所替代，连环的爆炸，惊慌逃散的人群，无序的车祸以及啃咬他人的丧尸，繁荣大都会转瞬沦陷。盖瑞费尽九牛二虎...

In 2011, Lisa Hepner and her husband Guy Mossman heard about a radical stem cell treatment for diabetes, a disease that shockingly kills more than five million people each year. Driven by a desire to ...